| Local Channels (Lawrence Satellite TV) | | 2 | 2 | WGBH | Programs on PBS include: The Woodwright's Shop, Life, The Tavis Smiley Show, American Masters, Bill Moyers Journal, Bob the Builder, Curious George, Cyberchase, Julia and Jacques: Cooking at Home, Nature, Mister Rogers' Neighborhood, Franny's Feet, and This Old House. | Local | Local |
| 4 | 4 | WBZ | Programs on CBS include: Busytown Mysteries, CSI: Miami, Harper's Globe, The Early Show, Arranged Marriage, NCIS: Los Angeles, The Good Wife, Survivor, Big Brother, PGA Tour Golf, Primetime Emmy Awards, The Late Late Show with Craig Ferguson, and CBS News Sunday Morning. | Local/HD | Local/HD |
| 5 | 5 | WCVB | Programs on ABC include: The View, Major League Soccer, American Music Awards, Better Off Ted, British Open, That's So Raven, Happy Town, All My Children, Nightline, The Bachelor, The Replacements, Mighty Morphin Power Rangers, and Rose Bowl Game. | Local/HD | Local/HD |
| 7 | 7 | WHDH | Programs on NBC include: NBC Nightly News, Parks and Recreation, Kentucky Derby, The Jay Leno Show, Saturday Night Live, Notre Dame home Football games, Last Call with Carson Daly, Today, The Office, PGA Tour Golf, Poker After Dark, 30 Rock, and Preakness Stakes. | Local/HD | Local/HD |
| 9 | 9 | WMUR | Programs on ABC include: The View, Major League Soccer, American Music Awards, Better Off Ted, British Open, That's So Raven, Happy Town, All My Children, Nightline, The Bachelor, The Replacements, Mighty Morphin Power Rangers, and Rose Bowl Game. | Local | Local |
| 11 | 11 | WENH | Programs on PBS include: The Woodwright's Shop, Life, The Tavis Smiley Show, American Masters, Bill Moyers Journal, Bob the Builder, Curious George, Cyberchase, Julia and Jacques: Cooking at Home, Nature, Mister Rogers' Neighborhood, Franny's Feet, and This Old House. | Local | Local |
| 25 | 25 | WFXT | Programs on FOX include: House, The Simpsons, The Wanda Sykes Show, Human Target, NFL on Fox/Fox NFL Sunday, The Conan O'Brien Show, Lie to Me, American Dad!, Bones, Major League Baseball on Fox, NAACP Image Awards, America's Most Wanted: America Fights Back, and Fox News Sunday. | Local/HD | Local/HD |
| 27 | 27 | WUNI | WUNI (UNI) | Local | Local |
| 38 | 38 | WSBK | WSBK (IND) | Local | Local |
| 44 | 44 | WGBX | Programs on PBS include: The Woodwright's Shop, Life, The Tavis Smiley Show, American Masters, Bill Moyers Journal, Bob the Builder, Curious George, Cyberchase, Julia and Jacques: Cooking at Home, Nature, Mister Rogers' Neighborhood, Franny's Feet, and This Old House. | Local | Local |
| - | 46 | WWDP | WWDP (ShopNBC) | - | Local |
| 50 | 50 | WZMY | WZMY (MNT) | Local | Local |
| 56 | 56 | WLVI | Programs on CW include: Melrose Place, 90210, One Tree Hill, The Tyra Banks Show, America's Next Top Model, Life Unexpected, Supernatural, Smallville, Gossip Girl, and The Vampire Diaries. | Local | Local |
| 60 | 60 | WNEU | WNEU (TMO) | Local | Local |
| 62 | - | WMFP | WMFP (IND) | Local | - |
| 66 | 66 | WUTF | WUTF (TFT) | Local | Local |
| 68 | - | WBPX | WBPX (ION) | Local | - |
|