| 6 | 6 | WPVI | Programs on ABC include: The Deep End, I Survived a Japanese Game Show, The Middle, Wipeout, General Hospital, ABC World News, Supernanny, Saturday Night College Football, Wife Swap, Mighty Morphin Power Rangers, Cougar Town, Country Music Association Awards, and Extreme Makeover: Home Edition. | Local/HD | Local/HD |
| 10 | 10 | WCAU | Programs on NBC include: Law & Order, Jacob Two-Two, The Marriage Ref, Days of our Lives, Law & Order: Special Victims Unit, Dragon, Law & Order: Criminal Intent, Trauma, Babar, Kentucky Derby, Notre Dame home Football games, Meet the Press, and Day One. | Local/HD | Local/HD |
| 12 | 12 | WHYY | Programs on PBS include: Hometime, Martha Speaks, American Masters, NOVA, Everyday Food, History Detectives, WordGirl, Frontline, Clifford the Big Red Dog, NOW, Independent Lens, GED Connection, and Design e2. | Local | Local |
| 17 | 17 | WPHL | WPHL (MNT) | Local | Local |
| 23 | - | NJN | Programs on PBS include: Hometime, Martha Speaks, American Masters, NOVA, Everyday Food, History Detectives, WordGirl, Frontline, Clifford the Big Red Dog, NOW, Independent Lens, GED Connection, and Design e2. | Local | - |
| - | 23 | WNJS | Programs on PBS include: Hometime, Martha Speaks, American Masters, NOVA, Everyday Food, History Detectives, WordGirl, Frontline, Clifford the Big Red Dog, NOW, Independent Lens, GED Connection, and Design e2. | - | Local |
| 28 | - | WFPA | WFPA (TFT) | Local | - |
| 29 | 29 | WTXF | Programs on FOX include: American Dad!, Past Life, The Cleveland Show, NFL on Fox/Fox NFL Sunday, The Conan O'Brien Show, America's Most Wanted: America Fights Back, Major League Baseball on Fox, The Wanda Sykes Show, Kitchen Nightmares, Bones, Human Target, New Year's Eve Live, and Bowl Championship Series. | Local/HD | Local/HD |
| 33 | - | WZPA | WZPA (AZA) | Local | - |
| 35 | 35 | WYBE | WYBE (ETV) | Local | Local |
| 39 | - | WLVT | Programs on PBS include: Hometime, Martha Speaks, American Masters, NOVA, Everyday Food, History Detectives, WordGirl, Frontline, Clifford the Big Red Dog, NOW, Independent Lens, GED Connection, and Design e2. | Local | - |
| 51 | 51 | WTVE | WTVE (IND) | Local | Local |
| 57 | 57 | WPSG | Programs on CW include: The Tyra Banks Show, Supernatural, The Vampire Diaries, Life Unexpected, America's Next Top Model, 90210, Smallville, Gossip Girl, Melrose Place, and One Tree Hill. | Local/HD | Local |
| 61 | - | WPPX | WPPX (ION) | Local | - |
| - | 62 | WWSI | WWSI (TMO) | - | Local |
| 65 | 65 | WUVP | WUVP (UNI) | Local | Local |
| 69 | 69 | WFMZ | WFMZ (IND) | Local | Local |
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